Status of genomic imprinting in mouse spermatids
نویسندگان
چکیده
منابع مشابه
Status of genomic imprinting in mouse spermatids.
The advent of human round spermatid microinjection (ROSI) into oocytes as a treatment for severe male infertility raises the question of whether spermatids have undergone all of the maturation processes necessary for normal development. It is particularly important to know whether spermatids have undergone correct genomic imprinting, which results in the parent-of-origin-specific expression of ...
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متن کاملGenomic Imprinting
BACKGROUND Genomic imprinting is the inheritance out of Mendelian borders. Many of inherited diseases and human development violates Mendelian law of inheritance, this way of inheriting is studied by epigenetics. AIM The aim of this review is to analyze current opinions and options regarding to this way of inheriting. RESULTS Epigenetics shows that gene expression undergoes changes more com...
متن کاملGenomic imprinting
Genomic imprinting is the epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner. If the allele inherited from the father is imprinted, it is thereby silenced, and only the allele from the mother is expressed. If the allele from the mother is imprinted, then only the allele from the father is expressed. Forms of genomic imprinting have been demonstrated...
متن کاملGenomic imprinting
Genomic imprinting is a normal form of gene regulation that causes a subset of mammalian genes to be expressed from one of the two parental chromosomes. Some imprinted genes are expressed from the maternally inherited chromosomes and others from the paternally inherited chromosomes. This means that the maternal and paternal genomes are not functionally equivalent and is the reason why both a ma...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1999
ISSN: 1460-2350
DOI: 10.1093/humrep/14.4.1050